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Compared with age-matched normals,patients with myotonic dystrophy(n=25) were more likely to have conduction abnormality(52%vs 9%),mitral valve prolapse(32%vs 9%),and wall motion abnormality(28%vs 0%)(all P<.05).Left ventricular ejection fraction and stroke volume were reduced compared with normals matched for age and heart rate(P<.05),whereas Doppler indexes of diastolic function were only marginally altered.Using multivariate analysis,the number of CTG repeats(range,69 to 1367;normal, |
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